| 541. Sherieta Lewis | Vocals | 1 |
| 541. Sheryl Crow | Guitar, Keys, Vocals | 1 |
| 541. Shiah Coore | Bass | 1 |
| 541. Shirley Caesar | Executive Producers, Vocals | 1 |
| 541. Shirley Collins | Vocals | 1 |
| 541. Shirley Simms | Ukulele, Vocals | 1 |
| 541. Shovels & Rope | Featured Artist | 1 |
| 541. Shubh Saran | Guitar | 1 |
| 541. Shucked | Featured Artist | 1 |
| 541. Shyamala Ramakrishna | Vocals | 1 |
| 541. Shyun | Guitar | 1 |
| 541. SiR | Vocals | 1 |
| 541. Sid Sriram | Vocals | 1 |
| 541. Sidney Hopson | Percussion | 1 |
| 541. Sierra Ferrell | Acoustic Guitar, Fiddle, Lead Vocals | 1 |
| 541. Sierra Hull | Guitar, Mandolin, Vocals | 1 |
| 541. Sierra Leone's Refugee All Stars | Featured Artist | 1 |
| 541. Sigrún Harðardóttir | Violin | 1 |
| 541. Silk-E The People's Champ aka Sherri Stack-A-Grip | Background Vocals | 1 |
| 541. Silvia Estrada | Guitarrón | 1 |
| 541. Sima Cunningham | Guitar, Vocals | 1 |
| 541. Simba | Bass | 1 |
| 541. Simba Scott | Bass | 1 |
| 541. Simeon Jones | Keys | 1 |
| 541. Simon Andermo | Auxiliary Percussion, Bass | 1 |