| 541. S'von | Keys | 1 |
| 541. S.G. Goodman | Electric Guitar, Vocals | 1 |
| 541. SA | Turntables, Vocals | 1 |
| 541. SAFA | Background Vocals | 1 |
| 541. SEVENTEEN | Featured Artist | 1 |
| 541. SFJAZZ Collective | Featured Artist | 1 |
| 541. SIX The Musical | Featured Artist | 1 |
| 541. SK | Keys | 1 |
| 541. SOAK | Featured Artist | 1 |
| 541. STOUT | Vocals | 1 |
| 541. SUGA | Vocals | 1 |
| 541. SUNSET BLVD. | Featured Artist | 1 |
| 541. SWV | Featured Artist | 1 |
| 541. Sa-Roc | Vocals | 1 |
| 541. Sabrina Carpenter | Vocals | 1 |
| 541. Sad13 | Featured Artist | 1 |
| 541. Sadler Vaden | Guitar | 1 |
| 541. Safa Alston | Choir | 1 |
| 541. Safa Ishmel-Muhammad | Vocals | 1 |
| 541. Saint Sister | Featured Artist | 1 |
| 541. Saintseneca | Featured Artist | 1 |
| 541. Sally Baby's Silver Dollars | Featured Artist | 1 |
| 541. Sally Gorski | Violin | 1 |
| 541. Sally Timms | Vocals | 1 |
| 541. Salvador Samano | Bass | 1 |